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50 True/False questions

  1. Parent training and behavioral interventions examples:Positive rewards for good behavior and structured limit setting are considered first line before meds in ages 3-5

          

  2. Side effects of guanfacine/ clonidine?- Bradycardia
    - Syncope
    - Rebound hypertension
    - Heart block
    - Sudden death

          

  3. Non-stimulant pharmacological therapy for ADHD (5 options)1. Methylphenidate
    2. Dexmethylphenidate
    3. Adderal
    4. Dextroamphetamine
    5. Lisdexanfetamine

          

  4. Benefits to once-daily stimulant formulations.- Convenient
    - Better medication adherence
    - Lower cost
    - Less insomnia
    - Potentially fewer growth effects

          

  5. T/F: Bupropion is FDA approved for the treatment of ADHD?- Imipramine
    - Despiramine
    - Nortriptyline

          

  6. Lisdexamfetamine brand name?Vyvanse

          

  7. The AAP considers ADHD a _____ disease, and this by definition has _____.Hyperthyroidism

          

  8. How many symptoms of inattention are needed for a diagnosis?6+ for at least 6 months
    MUST negatively impact social/ other activities

          

  9. When considering ADHD it is important to rule out _____.Hyperthyroidism

          

  10. Bupropion adverse effects?- Nausea
    - Rash
    - Should not be used in children (or any patient) with seizure disorder or eating disorder
    - May exacerbate tics

          

  11. Non-pharmacologic therapy for ADHD?Psychotherapy
    - Educational
    - Cognitive
    - Behavioral

          

  12. TCAs used in the treatment of ADHD?- Iron
    - Zinc
    - Omega 3
    - Additive/Preservative- Free diet
    - Oligoantigenic elimination diet

          

  13. T/F: Studies showed that patients experienced more side effects with buproprion than with methylphenidate.True

          

  14. ADHD is characterized by the DSM-V with 2 main things.Psychosis/Mania
    Aggression or violent behavior
    Severe anxiety/panic attacks
    Tactile hallucinations

          

  15. T/F: Lisdexanfetamine is a prodrug?True

          

  16. First degree relatives of an individual with ADHD are _____ times more likely to have ADHD.4-8

          

  17. Drugs that are central alpha-2 adrenergic agonists (2)Guanfacine ER (Tenex)
    Clonidine ER (Catapres)

          

  18. T/F: Patients who have a history of schizophrenia have a contraindication to stimulant ADHD drugs?True

          

  19. T/F: TCAs have the highest risk of cardiac side effects?1. Combined type
    2. Hyperactive/Impulsive
    3. Predominantly inattentive

          

  20. There is a universal belief that avoidance of ____ and ____ improves ADHD symptoms.Last

          

  21. Besides medications, it is important for patients with ADHD to undergo _______.Behavioral interventions

          

  22. Stimulants are considered to be ______ over psychotherapy.Last

          

  23. 2 "classes" of pharmacological therapy for ADHDPsychotherapy
    - Educational
    - Cognitive
    - Behavioral

          

  24. Bupropion brand nameWellbutrin

          

  25. MOA for methylphenidate and amphetamines?- GI upset
    - Psych/ cardiac side effects
    - Warning for severe liver injury
    - Fatigue, sedation
    - FDA warning for new-onset suicidality

          

  26. Which mineral supplements are recommended in patient with ADHD?Iron
    Zinc

          

  27. Psych. adverse effects of stimulants.- ADHD stimulants can effect growth, but the effects are minimal/insignificant in children
    - Amphetamines may be associated with more growth effects than methylphenidate
    - Children should be given a drug-free trial every year
    - Not considered a contraindication

          

  28. Adverse effects of amoxetine?- GI upset
    - Psych/ cardiac side effects
    - Warning for severe liver injury
    - Fatigue, sedation
    - FDA warning for new-onset suicidality

          

  29. T/F: the therapeutic benefit of amoxetine may not be seen for 6-8 weeks.Specific
    (e.g. be able to sit an a chair for 20 mins, completes homework assignments)

          

  30. Which pharmacological therapy is considered second line?Psychotherapy
    - Educational
    - Cognitive
    - Behavioral

          

  31. Non-stimulant drug approved for use in ADHD in adults?Amoxetine

          

  32. Amoxetine brand name?Strattera

          

  33. What pharmacological therapy is considered first line?Stimulants

          

  34. What class are ADHD medication?1. Combined type
    2. Hyperactive/Impulsive
    3. Predominantly inattentive

          

  35. Which form of stimulants are the preferred treatment?Delayed release drugs
    (Once-daily formulations are preferred)

          

  36. What is considered the best option for treatment for a patient with ADHD?Combination of behavioral therapy and pharmacological therapy

          

  37. Bupropion MOA?SNRI

          

  38. TCAs are considered ____ line treatment for ADHD.Last

          

  39. The desired outcomes of treatment must be _____.- Imipramine
    - Despiramine
    - Nortriptyline

          

  40. Lisdexamfetamine advantages?- Longer time to onset of effectiveness
    - May provide a smoother blood level compared with extended-release formulations
    - It is intended to pose less abuse potential

          

  41. What are the 3 types of ADHD?1. Combined type
    2. Hyperactive/Impulsive
    3. Predominantly inattentive

          

  42. Cardiac adverse effects of stimulantsSudden unexplained death has been added to ADHD stimulant drug labeling
    - Increased heart rate
    - Increased BP
    - Caution in patients with known cardiac abnormalities
    - Consider baseline ECG if history suggests cardiac abnormality

          

  43. Stimulant pharmacological therapy (5 options)1. Methylphenidate
    2. Dexmethylphenidate
    3. Adderal
    4. Dextroamphetamine
    5. Lisdexanfetamine

          

  44. How many symptoms of hyperactivity/impulsivity are needed for a diagnosis?6+ for at least 6 months
    MUST negatively impact social/ other activities

          

  45. Side effects of IR clonidine?- Bradycardia
    - Syncope
    - Rebound hypertension
    - Heart block
    - Sudden death

          

  46. Amoxetine MOA?SNRI

          

  47. Diet treatment for ADHD?- Imipramine
    - Despiramine
    - Nortriptyline

          

  48. Onset of symptoms must occur before _____.- Iron
    - Zinc
    - Omega 3
    - Additive/Preservative- Free diet
    - Oligoantigenic elimination diet

          

  49. Central Alpha-2 adrenergic agonist MOA?Inhibit NE release presynaptically
    Increase blood flow to the PFC postsynaptically

          

  50. Growth adverse effects of stimulants- ADHD stimulants can effect growth, but the effects are minimal/insignificant in children
    - Amphetamines may be associated with more growth effects than methylphenidate
    - Children should be given a drug-free trial every year
    - Not considered a contraindication