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  1. kernicterus
  2. autosomal dominant inheritance accounts for
  3. toxoplasmosis
  4. x-linked inheritance accounts for
  5. ____ of genetic hearing loss is part of syndrome
  6. cytomegalovirus (CMV)
  7. leading cause of sensorineural hearing loss in children
  8. female to male ratio for Enlarged Vestibular Aqueduct Syndrome
  9. congenital infection
  10. enlarged vestibular aqueduct syndrome
  11. ototoxic medications
  12. presbycusis
  13. noise induced hearing loss
  14. leading cause of sensorineural hearing loss in adults
  15. retrocochlear disorders
  16. pendred's syndrome
  17. examples of autosomal recessive inheritance
  18. acoustic neuroma/vestibular schawnnoma
  19. characteristics of presbycusis
  20. other acquired causes of sensorinerual hearing loss
  21. many sensorineural disorders are
  22. bacterial meningities
  23. meniere's disease
  24. ____ of congential hearing losses are genetic
  25. symptoms of neuroma/vestibular schawnnoma
  26. syphilis
  27. autosomal recessive accounts for
  28. enlarged vestibular aqueduct syndrom is commonly identificied
  29. hyperbilirubinemia
  30. incidence of severe sensorineural hearing loss
  31. rubella
  32. measles
  33. characteristics of multiple sclerosis
    and cerebovascular accident/stroke
  34. autosomal recessive inheritance
  35. characteristics of acoustic neuroma/vestibular schawnnoma
  36. usher's syndrome
  37. autosomal dominant inhertitance
  38. apirin affects
  39. non-genetic causes of hearing loss
  40. waardenburg's syndrome
  41. symptoms of meniere's disease
  42. mumps
  43. characteristics of nose induced hearing loss
  44. types of inheritance
  45. accumulation of drug in blood affects
  46. herpes simplex virus
  47. postnatal infections are associated with
  48. treatment for meneire's disease
  1. a -excess fluid in the inner ear
    -progressive or fluctuating, low-frequency HL
    -bilateral or unilateral (thought to be more often unilateral)
  2. b 30%
  3. c hearing loss and difficutly w/ speech recognition in noisy conditions
  4. d 5-20%
  5. e age-related hearing loss (50+)
  6. f -autosomar dominant inheritance
    -autosomal recessive inheritcane
    -x-linked inhertitance (passed from mother to son)
  7. g postnatal infections; rubeola
  8. h -almost always unilateral
    -affects high frequencies first
  9. i 1/2
  10. j -ototoxic medications
    -meniere's desease
    -noise exposure
    -genetic causes
    -otitis media
  11. k -Congenital Infections: TRCHs
    -hyperbilirubinemia with kernicterus
    -trauma at birth
    -medication during birht
    -low birth weight bc of byperbilirubinemia
    -postnatal infections: bacterial mningitis, mumps, measles (rubeola)
    -ototoxic medications
    -meniere's disease
    -noise exposure
    -genetic causes
    -otitis media
  12. l autosomal dominant inheritance; absence of organ of corti and atrophy of spiral ganglion; accompanied by:
    -white forelock of hair
    -iris bicolor or heterochromia
  13. m postnatal infections; common causes of unilateral sever-profund sensorineural
  14. n genetic (endogenous)
  15. o goiter and profound deafness
  16. p attack inner ear through bloodstream---high frequencies affected first
    -aminoglycoside antibiotics (streptomycin[vestubulo toxin], neomycin, gentamicin, kanamycin, tobramycin [cochlea toxin)
    -diuretics (especially furosemide)
    -chemotherapeutic agents (platinum based agents, e.g., cisplatinin, carboplatin)
  17. q Toxoplasmosis
  18. r 80$ of all genetic hearing loss
    -the majority
  19. s symptom of Pendred syndrome, associated with mondini cochlear dysplasia
    -'reflux' of endolymph through abnormally large endolymphatic duct and vestibular aqueduct (bony canal leading from inner ear to cranial cavity) causes damage to cochlear structures in scala media (akin to meniere's mechanism), endolymphatic sac thought to regulate fluid pressure—increase in CSF pressure may cause reflux ('blowing a trumpet', weight lifting, diving, air plane flight) (someitme progressive, sometimes suddenly)
    -initially in high frequencies
  20. t gene present in both parents
    -25% change of any child inheriting hearing loss
    -children can be carriers
  21. u low frequencies
  22. v benign, slow-growing tumor compressing the nerve [compresses brain stem functions]
    -(must be removed surgically)
    -most common tumor of temporal bone
  23. w episodic vertigo **
    tinnitus, feeling of fullness in the ear
  24. x 20% of all genetic hearing loss
  25. y 1. usher's syndrome
    2. pendred's syndrome
    3. enlarged vestibular aqueduct syndrome
  26. z hair cell and other cochlera structures dmaged or destroyed
    -dependent on intensity, spectrum of noise, duration of exposure & individual resistance (not necessarily related to loudness of noise)
  27. aa congenital deafness and progressive loss of vision (retinitis pigmentosa) leading to eventual blindness
  28. ab -acoustic neuroma/vestibular schawnnoma
    -multiple sclerosis
    -cerebovascular accident/stroke
  29. ac vestibular impaiment
  30. ad too much bilirubin in the blood
    -hearing loss occurs in sever cases with kernicterus
  31. ae base of cochlea (high frequencies)
  32. af tinnitus & dizziness common symptoms
  33. ag sexually transmitted, passed to fetus in utero
  34. ah postnatal infection; leading cause of acquired childhood severe sensorineural hearing loss
    -can affect cochlear, audiotry nerve, CANS (inflammation causes ossification inside cochlear)
  35. ai 2-3% of genetic hearing loss
  36. aj passed from the mother to the child via the bloodstream and/or contact with the birth canal; most common viral disease known to cause hearing loss
    -90% of symptomatic children who survive will exhibit complications, the majority will have hearing loss
    -HL is usually progressive, less often unilateral than bilateral, most often severe to profound
  37. ak caused by parasite transmitted to child via placenta (not viral, it's a paraiste)
  38. al transmitted to child in eurtero
    -may manifest itself up to 60 years later, if syphilis shows < 10 yrs, profound hearing loss & bilateral with sudden onset
  39. am gene exists on one off 22 pairs of non-sex determining chromosomes
    -hearing loss bc of heritence for EITHER parent
    -50% chance of any child inheriting hearing loss
    punett sq of Dd with dd
  40. an 3:2
  41. ao noise exposure and presbycusis
  42. ap maternal-contracted, passed to child through placenta prenatally; typically bilateral, severe to profound loss, with worst hearing in the mid frequencies (cookie bite configuration)

    -earlier infection increases the chance of hearing loss
    -possibly accompanied by heart/kidney defects, visual impairment (german measles)
  43. aq -Low-sodium diets
    -Sedatives, tranquilizers
    -Vestibular suppressants (e.g., Antivert); drugs that suppress the vestiulus system
    -Endolymphatic shunt surgery
    -Destruction of the labyrinth/cutting the auditory nerve
  44. ar -Almost always bilateral (unless very mild), but can be asymmetrical
    -Affects frequencies between 3000 & 6000 Hz first (doesn't affect outer/middle ear, it affects cochlear
    -Notched configuration
  45. as genetic causes and otitits media
  46. at bile deposits in CNS at cochlear nuclei
  47. au children with sneorineural hearing loss of unknonw etiology
    -often bilatreal
    -sensorineural hearing loss at birth or onset in childhood
  48. av -affects cochlea, but can also affect auditory nerve and CANS
    -high frequencies affected first
    -bilateral, symmetrical, typically mild to moderate hearing loss